dc.contributor |
Universitat de Vic. Càtedra de Cures Pal·liatives |
|
dc.contributor.author |
Molist Brunet, Núria |
|
dc.contributor.author |
Sevilla Sánchez, Daniel |
|
dc.contributor.author |
Amblàs-Novellas, Jordi |
|
dc.contributor.author |
Codina Jané, Carles |
|
dc.contributor.author |
Gómez-Batiste, Xavier |
|
dc.contributor.author |
McIntosh, J. |
|
dc.contributor.author |
Espaulella Panicot, Joan |
|
dc.date.accessioned |
2014-03-05T12:46:34Z |
|
dc.date.available |
2014-03-05T12:46:34Z |
|
dc.date.created |
2014 |
|
dc.date.issued |
2014 |
|
dc.identifier.citation |
Molist Brunet, N., Sevilla-Sánchez, D., Amblàs Novellas, J., Codina Jané, C., Gómez-Batiste, X., McIntosh, J., Espaulella Panicot, J. (2014). Optimizing drug therapy in patients with advanced dementia:
A patient-centered approach. European Geriatric Medicine, 5 ( 1 ), 66-71. |
ca_ES |
dc.identifier.issn |
1878-7649 |
|
dc.identifier.uri |
http://hdl.handle.net/10854/2759 |
|
dc.description.abstract |
Background: Advanced dementia is a prevalent health problem in geriatric patients. These patients
usually suffer from several chronic diseases, frequently leading to an end-of-life situation lasting months
or years, generating complex and often inappropriate medication regimens.
Objectives: Describe the re-orientation of drug therapy in patients with advanced dementia utilizing a
systematic medication review process.
Methods: This non-experimental pre-post analysis included all patients with advanced dementia
admitted to acute geriatric unit (AGU) over one year. Medications were reviewed by a multidisciplinary
team and together with the patient caregivers; new therapeutic objectives based on end-of-life care
principles were established. Medications were classified as preventive, therapeutic, or symptomatic. The
average number of medications per patient pre- and post-admission was compared.
Results: We included 73 patients (mean age 86.1 years, mean Barthel Index: 14.5/100). At admission,
patients had a mean of 7.27 drugs compared to 4.82 at discharge (66.85% reduction, P < 0.05). The main
drugs withdrawn were cardiovascular and hematological (35.76%). Drugs for prevention decreased by
66.85% (from 1.8 to 0.6, P < 0.05) and those for symptomatic care decreased by 17,52% (from 2.34 to 1.93,
P < 0.05).
Conclusion: Medication therapy plans in patients with advanced dementia often do not meet their
therapeutic goals. The proposed methodology is a useful tool to assess therapeutic appropriateness. |
ca_ES |
dc.format |
application/pdf |
|
dc.format.extent |
6 p. |
ca_ES |
dc.language.iso |
eng |
ca_ES |
dc.publisher |
Elsevier Masson |
ca_ES |
dc.rights |
(c) 2014 Elsevier. Published article is available at: http://dx.doi.org/10.1016/j.eurger.2013.10.011 |
|
dc.subject.other |
Demència senil |
ca_ES |
dc.subject.other |
Medicaments |
ca_ES |
dc.title |
Optimizing drug therapy in patients with advanced dementia: A patient-centered approach |
ca_ES |
dc.type |
info:eu-repo/semantics/article |
ca_ES |
dc.identifier.doi |
https://doi.org/10.1016/j.eurger.2013.10.011 |
|
dc.relation.publisherversion |
http://www.sciencedirect.com/science/article/pii/S1878764913009261 |
|
dc.rights.accessRights |
info:eu-repo/semantics/closedAccess |
ca_ES |
dc.type.version |
info:eu-repo/publishedVersion |
ca_ES |
dc.indexacio |
Indexat a SCOPUS |
|
dc.indexacio |
Indexat a WOS/JCR |
ca_ES |