Browsing Articles by Author "Pardo Carrasco, Leonardo"

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Influence of the g conformation of Ser and Thr on the structure of transmembrane helices

Deupi, Xavier; Olivella, Mireia; Sanz, Arantxa; Dölker, Nicole; Campillo Grau, María Mercedes; Pardo Carrasco, Leonardo (Elsevier, 2010)

In order to study the influence of Ser and Thr on the structure of transmembrane helices we have analyzed a database of helix stretches extracted from crystal structures of membrane proteins and an ensemble of model ...
Relation between sequence and structure in membrane proteins

Olivella, Mireia; González, Ariadna; Pardo Carrasco, Leonardo; Deupi, Xavier (Oxford University Press, 2013)

Motivation: Integral polytopic membrane proteins contain only two types of folds in their transmembrane domains: -helix bundles and b-barrels. The increasing number of available crystal structures of these proteins ...
TMalphaDB and TMbetaDB: web servers to study the structural role of sequence motifs in α-helix and β-barrel domains of membrane proteins

Perea, Marc; Lugtenburg, Ivan; Mayol, Eduardo; Cordomí Montoya, Arnau; Deupi, Xavier; Pardo Carrasco, Leonardo; Olivella, Mireia (BioMed Central, 2015)

Background Membrane proteins represent over 25 % of human protein genes and account for more than 60 % of drug targets due to their accessibility from the extracellular environment. The increasing number of available ...

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