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Browsing Articles by Author "Pérez-Alvarez, Susana"

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Alternative Effector-Function Profiling Identifies Broad HIV-Specific T-Cell Responses in Highly HIV-Exposed Individuals Who Remain Uninfected

Ruiz-Riol, Marta; Llano, Anuska; Ibarrondo, Javier; Zamarreño, Jennifer; Yusim, Karina; Back, Vanessa; Mothe, B.; Pérez-Alvarez, Susana; Fernández, M.A.; Requena, Gerard; Meulbroek, Michael; Pujol, Ferran; Leon, Agathe; Cobarsi, P.; Korber, Bette T.; Clotet, Bonaventura; Ganoza, C.; Sánchez, Jorge; Coll, J.; Brander, Christian (Oxford University Press, 2015)

The characterization of host immune responses to human immunodeficiency virus (HIV) in HIV controllers and individuals with high exposure but seronegativity to HIV (HESN) is needed to guide the development of effective ...
FARMS: A New Algorithm for Variable Selection

Pérez-Alvarez, Susana; Gómez, Guadalupe; Brander, Christian (2015)

Large datasets including an extensive number of covariates are generated these days in many different situations, for instance, in detailed genetic studies of outbreed human populations or in complex analyses of immune ...
HLA-BM35-PX and HLA-BM35-PY subtype differentiation does not predict observed differences in level of HIV control in a Peruvian MSM cohort

Olvera, Alex; Ganoza, C.; Pérez-Alvarez, Susana; Hildebrand, William; Sánchez, Jorge; Brander, Christian (Lippincott Williams & Wilkins, 2014)
Improved Prediction of Salvage Antiretroviral Therapy Outcomes Using Ultrasensitive HIV-1 Drug Resistance Testing

Pou, Christian; Noguera-Julian, Marc; Pérez-Alvarez, Susana; Garcia, Federico; Delgado, Rafael; Dalmau, David; Álvarez-Tejado, Miguel; González, Dimitri; Chueca, Natalia; Sayada, Chalom; Pulido, Federico; Ibáñez, Laura; Rodriguez Carbonell, Cristina; Casadellà, Maria; Santos, José R.; Ruiz, Lídia; Clotet, Bonaventura; Paredes, Roger (Oxford University Press, 2014)

Background. The clinical relevance of ultrasensitive human immunodeficiency virus type 1 (HIV-1) genotypic resistance testing in antiretroviral treatment (ART)-experienced individuals remains unknown. Methods. This was ...
Monotherapy with boosted PIs as an ART simplification strategy in clinical practice

Santos, José R.; Llibre, Josep M.; Berrio-Galan, Daniel; Bravo, Isabel; Miranda, Cristina; Pérez-Alvarez, Susana; Pérez Alvarez, Núria; Paredes, Roger; Clotet, Bonaventura; Moltó, José (Oxford University Press, 2015)

Background: Data on the efficacy of simplifying therapy using darunavir/ritonavir and lopinavir/ritonavir monotherapy in clinical practice remain limited. Methods: A retrospective single-centre study including patients ...
The HLA-C*04:01/KIR2DS4 gene combination and human leukocyte antigen alleles with high population frequency drive rate of HIV disease progression

Olvera, Alex; Pérez-Alvarez, Susana; Ibarrondo, Javier; Ganoza, C.; Lama, Javier R.; Lucchetti, Aldo; Cate, Steven; Hildebrand, William; Bernard, Nicole; Gómez, Guadalupe; Sanchez, Jorge; Brander, Christian (Wolters Kluwer Health, 2015)

Objective: The objective of this study is to identify human leukocyte antigen (HLA) class I and killer-cell immunoglobulin-like receptor (KIR) genotypes associated with different risks for HIV acquisition and HIV disease ...

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