Membrane proteins are a large group of proteins that play an essential role in the cell. This group includes receptors, ion channels, transporters, and enzymes, which account for 25% of the proteins in the human genome. ...

We propose a novel multifactor dimensionality reduction method for epistasis detection in small or extended pedigrees, FAM-MDR. It combines features of the Genome-wide Rapid Association using Mixed Model And Regression ...

Summary: We describe mbmdr, an R package for implementing the model-based multifactor dimensionality reduction (MB-MDR) method. MB-MDR has been proposed by Calle et al. as a dimension reduction method for exploring ...

En este doctorado industrial, el objetivo era cumplir los objetivos innovadores de Whole Genix, que incluyen: dominar los protocolos de secuenciación masiva de próxima generación (en inglés next-generation sequencing, NGS), ...