It has been previously described that although phosphorylation of S32,36 is the instructive mark that targets IKBα for K21,22 ubiquitination and its subsequent degradation by the proteasome, K21,22 sumoylation protects ...

El carcinoma NUT (NC) és un tipus de càncer humà rar i molt agressiu provocat per reordenacions genòmiques, que resulten en fusions entre el gen específic de testicles NUT i gens codificants per reguladors epigenètics, ...