Association between polymorphic inversions and miRNA in cancer data

Ramírez Priego, Patrícia

Home
→
Docència
→
Treballs de l'alumnat
→
Treballs de Fi de Màster
→
Màster Universitari en Anàlisi de Dades Òmiques
→
View Item

dc.contributor	Universitat de Vic - Universitat Central de Catalunya. Facultat de Ciències i Tecnologia
dc.contributor	Universitat de Vic - Universitat Central de Catalunya. Màster Universitari en Anàlisi de Dades Òmiques
dc.contributor.author	Ramírez Priego, Patrícia
dc.date.accessioned	2019-02-07T17:06:16Z
dc.date.available	2019-02-07T17:06:16Z
dc.date.created	2016-09
dc.date.issued	2016-09
dc.identifier.uri	http://hdl.handle.net/10854/5677
dc.description	Curs 2015-2016
dc.description.abstract	Inversion polymorphisms is a mechanism that involves a change in the orientation of a DNA segment within a chromosome, but there is still a lack of their association with disease. However, recently developed computational methods have enabled to discover new human inversion polymorphisms and their association with complex diseases. To overcome this lack of knowledge, we aimed to investigate the effect of four well characterized inversions (8p23, 15q24.2, 16p11.2 and 17q23.31) on miRNA expression in cancer samples. We perform an association analysis between inversion and miRNA expression and Gene Ontology enrichment analysis using different R packages. Our preliminary findings show that there are an association between miRNA expression and cancer, and that it affects important pathways related to cancer.	es
dc.format	application/pdf	es
dc.format.extent	54 p.	es
dc.language.iso	eng	es
dc.rights	Aquest document està subjecte a aquesta llicència Creative Commons	es
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/es/	es
dc.subject.other	Bioinformàtica	es
dc.subject.other	Càncer	es
dc.subject.other	ADN	es
dc.title	Association between polymorphic inversions and miRNA in cancer data	es
dc.type	info:eu-repo/semantics/masterThesis	es
dc.description.version	Director/a: Juan Ramón González Co-director/a: Josep Maria Jurado
dc.description.version	Supervisor:
dc.rights.accessRights	info:eu-repo/semantics/openAccess	es