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Prevalence of Ischemic Heart Disease and Management of Coronary Risk in Daily Clinical Practice: Results from a Mediterranean Cohort of HIV-Infected Patients

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dc.contributor Universitat de Vic - Universitat Central de Catalunya. Càtedra de la Sida i Malalties Relacionades
dc.contributor.author Echeverria, Patricia
dc.contributor.author Domingo, Pere
dc.contributor.author Llibre, Josep M.
dc.contributor.author Gutierrez, Mar
dc.contributor.author Mateo, Gracia
dc.contributor.author Puig, Jordi
dc.contributor.author Bonjoch, Anna
dc.contributor.author Pérez Alvarez, Núria
dc.contributor.author Sirera, Guillem
dc.contributor.author Clotet, Bonaventura
dc.contributor.author Negredo, Eugenia
dc.date.accessioned 2014-09-16T14:59:20Z
dc.date.available 2014-09-16T14:59:20Z
dc.date.created 2014
dc.date.issued 2014
dc.identifier.citation Echeverria, P., Domingo, P., Llibre, J., Gutierrez, M., Mateo, G., Puig, J., et al. (2014). Prevalence of ischemic heart disease and management of coronary risk in daily clinical practice: Results from a mediterranean cohort of HIV-infected patients. Biomed Research International, , 823058. http://dx.doi.org/10.1155/2014/823058 ca_ES
dc.identifier.issn 2314-6133
dc.identifier.uri http://hdl.handle.net/10854/3256
dc.description.abstract There are conflicting data on the prevalence of coronary events and the quality of the management of modifiable cardiovascular risk factors (CVRF) inHIV-infected patients. Methods.We performed a retrospective descriptive study to determine the prevalence of coronary events and to evaluate the management of CVRF in a Mediterranean cohort of 3760 HIV-1-infected patients from April 1983 through June 2011. Results.We identified 81 patients with a history of a coronary event (prevalence 2.15%); 83% of them suffered an acute myocardial infarction. At the time of the coronary event, CVRF were highly prevalent (60.5% hypertension, 48% dyslipidemia, and 16% diabetes mellitus).OtherCVRF, such as smoking, hypertension, lack of exercise, and body mass index, were not routinely assessed. After the coronary event, a significant decrease in total cholesterol (𝑃� = 0.025) and LDLcholesterol (𝑃� = 0.004) was observed. However, the percentage of patients whomaintained LDL-cholesterol > 100mg/dL remained stable (from 46% to 41%, 𝑃� = 0.103). Patients using protease inhibitors associated with a favorable lipid profile increased over time (𝑃� = 0.028). Conclusions.The prevalence of coronary events in our cohort is low. CVRF prevalence is high and theirmanagement is far from optimal. More aggressive interventions should be implemented to diminish cardiovascular risk in HIV-infected patients. en
dc.format application/pdf
dc.format.extent 9 p. ca_ES
dc.language.iso eng ca_ES
dc.publisher Hindawi Publishing Corporation ca_ES
dc.rights Aquest document està subjecte a aquesta llicència Creative Commons ca_ES
dc.rights.uri http://creativecommons.org/licenses/by/3.0/es/ ca_ES
dc.subject.other Sida -- Tractament ca_ES
dc.title Prevalence of Ischemic Heart Disease and Management of Coronary Risk in Daily Clinical Practice: Results from a Mediterranean Cohort of HIV-Infected Patients en
dc.type info:eu-repo/semantics/article ca_ES
dc.identifier.doi https://doi.org/10.1155/2014/823058
dc.relation.publisherversion http://www.hindawi.com/journals/bmri/2014/823058/
dc.rights.accesRights info:eu-repo/semantics/openAccess ca_ES
dc.type.version info:eu-repo/publishedVersion ca_ES
dc.indexacio Indexat a SCOPUS
dc.indexacio Indexat a WOS/JCR ca_ES

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