Browsing Articles by Author "Agulló, Luis"

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Computational exploration of the binding mode of heme-dependent stimulators into the active catalytic domain of soluble guanylate cyclase.

Agulló, Luis; Gutiérrez de Teran, H.; Garcia-Dorado, D.; Villà-Freixa, Jordi; Buch, Ignasi (Wiley Periodicals, 10-2016)

Soluble guanylate cyclase (sGC), the main target of nitric oxide (NO), has been proven to have a significant role in coronary artery disease, pulmonary hypertension, erectile dysfunction, and myocardial infarction. One of ...
Proteoliposomal formulations of an HIV-1 gp41-based miniprotein elicit a lipid-dependent immunodominant response overlapping the 2F5 binding motif

Molinos-Albert, Luis M.; Bilbao, Eneritz; Agulló, Luis; Marfil, Sílvia; García, Elisabet; Rodríguez de la Concepción, Maria L.; Izquierdo Useros, Nuria; Vilaplana, Cristina; Nieto-Garai, Jon A.; Contreras, F. Xabier; Floor, Martin; Cardona, Pere J.; Martinez Picado, Francisco Javier; Clotet, Bonaventura; Villà-Freixa, Jordi; Lorizate, M.; Carrillo, Jorge; Blanco, Julià (Nature Publishing Group, 2017)

The HIV-1 gp41 Membrane Proximal External Region (MPER) is recognized by broadly neutralizing antibodies and represents a promising vaccine target. However, MPER immunogenicity and antibody activity are influenced by ...

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