Inversion polymorphisms is a mechanism that involves a change in the orientation of a DNA segment within a chromosome, but there is still a lack of their association with disease. However, recently developed computational ...

this final project, we show the results of a strain engineering strategy for heterologous protein production in the host organism Pichia pastoris. P. pastoris is a yeast with a huge industrial potential due to its set of ...

Background: The field of transcriptomics has developed an exponential growth in the last years thanks to the advances in high throughput RNA sequencing (RNAseq), which is becoming more popular as the cost is decreasing. ...

Background: During the last decade, multiple efforts have been dedicated to the modelling of an accurate predictor of age based on DNA methylation status(1–4). However, most of current models have been trained and therefore ...

Introducció: Des del seu descobriment l’any 2011, les proves de detecció amb ADN lliure per alteracions fetals genètiques han sigut una molt bona alternativa als mètodes tradicionals. Aquest treball fa una revisió bibliogràfica ...

Tight junctions are present in all epithelial tissues and are involved in several processes of signalling and barrier formation. Although the proteins that compose them are known, some of the exact mechanisms that drive ...

La identificació taxonòmica d’espècies properes requereix en ocasions la intervenció d’un taxònom expert en el grup zoològic en qüestió, i sovint hi ha de dedicar un esforç important. Actualment, s’han establert diferents ...

Alzheimer disease (AD) is associated with distinctive changes in DNA methylation patterns. DNA methylation is a chemical modification that is involved in gene silencing. These modifications give rise to heritable changes ...