The characterization of the small transcriptome reveals a generalized down-regulation both at premanifest and manifest stages, which brings out the course of Huntington’s disease. Partial Least Squares Discriminant Analysis ...

So far research has traditionally identified a negative correlation between miRNA and its respective mRNA targets. However, recent research has stated that some neuronal miRNA don’t correlate negatively with their targets ...

Background: The field of transcriptomics has developed an exponential growth in the last years thanks to the advances in high throughput RNA sequencing (RNAseq), which is becoming more popular as the cost is decreasing. ...

The Piwi-interacting RNA (piRNA) system is an evolutionarily conserved mechanism involved in the control of transposable elements and maintenance of genomic stability, especially in germ line cells and in early embryo ...

Background The relationship between host microRNAs (miRNA), viral control and immune response has not yet been elucidated in the field of HIV. The aim of this study was to assess the differential miRNA profile in CD8+ ...