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Browsing by Author "Olivella, Mireia"

Browsing by Author "Olivella, Mireia"

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  • Deupi, Xavier; Olivella, Mireia; Sanz, Arantxa; Dölker, Nicole; Campillo Grau, María Mercedes; Pardo Carrasco, Leonardo (Elsevier, 2010)
    In order to study the influence of Ser and Thr on the structure of transmembrane helices we have analyzed a database of helix stretches extracted from crystal structures of membrane proteins and an ensemble of model ...
  • Olivella, Mireia; González, A.; Pardo Carrasco, Leonardo; Deupi, Xavier (Oxford University Press, 2013)
    Motivation: Integral polytopic membrane proteins contain only two types of folds in their transmembrane domains: -helix bundles and b-barrels. The increasing number of available crystal structures of these proteins ...
  • Olivella, Mireia; Caltabiano, Gianluigi; Cordomí, Arnau (Biomed Central, 2013)
    Abstract Background: The CWxP motif of transmembrane helix 6 (x: any residue) is highly conserved in class A GPCRs. Within this motif, W6.48 is a big star in the theory of the global “toggle switch” because of its key ...
  • Perea, Marc; Lugtenburg, Ivan; Mayol, Eduardo; Cordomí, Arnau; Deupi, Xavier; Pardo Carrasco, Leonardo; Olivella, Mireia (BioMed Central, 2015)
    Background Membrane proteins represent over 25 % of human protein genes and account for more than 60 % of drug targets due to their accessibility from the extracellular environment. The increasing number of available ...

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